Rubes by Leigh Rubin.
This comic is very reminiscent of Gary Larson's "Far Side", and not just due to the single-panel style. The humor is off-beat, in a great way.
Click to enlarge.
At the main 'Rubes' site you can find more information about the creator, Leigh Rubin, a color gallery, an online store with collections of the comic and a contact page for Mr. Rubin.
Hope you enjoy the comic!
